Literature Review Matrix of Articles Used in Critical Appraisal

Literature Review Matrix of Articles Used in Critical Appraisal

Table 1

Literature Review Matrix of Articles Used in Critical Appraisal

Study Citation and Level of Evidence Purpose Design Sample Measurement tool(s)/Instrument(s) Statistical Analysis Key Findings
Berkhof, F., Hertog, N., Uil, S., Kerstjens, H.,& Berg, J. (2013). Azithromycin and cough-specific health status in patients with chronic obstructive pulmonary disease: A randomized control trial. Respiratory Research, 14 (125).

Level II

Assess the effects of prophylactic azithromycin on cough-specific health statuses in COPD patients with chronic productive cough over the course of three months. Single-center parallel group randomized double-blind placebo controlled trial 84 adults > 40 years of age with COPD GOLD stage > 2 and chronic productive cough.

Azithromycin therapy group (n=42) and placebo group (n=42)

Leicester Cough Questionnaire (LCQ)

St. George’s Respiratory Questionnaire (SGRQ)

Short Form 36 (SF-36)

Literature Review Matrix of Articles Used in Critical Appraisal

 

 

Intention-to-treat analysis.

Log-rank test.

Kaplan-Meier curves.

Chi-square tests.

ANCOVA analysis.

LCQ scores improved significantly in azithromycin group participants with low baseline scores 1.3 + 0.5 (95% CI 0.3; 2.3, p=0.001). Exacerbation frequency was reduced in azithromycin group.
Lee, H., Kim, S., Sok, S. (2016). Effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression of Korean older adults with mild cognitive impairment in care facilities. Journal of Nursing Scholarship 48 (3) 229-231.

Level III

Examine effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression Quasi-experimental pretest-postest control group 48 adults > 65 years with mild cognitive impairment (MCI)

Intervention group (n=24); Control group (n=24)

Serum homocysteine levels

Geriatric Depression Scale Short Form Korean Version (GDSSF-K)

Mini Mental State Examination-Korean (MMSE-K)

 

Two group t test

Chi-square test for association

Fisher’s exact test

Intervention group had significantly increased cognitive function  compared to control group (F=3.624, p=.021); significant decrease serum homocysteine level (F=6.974, p=.001) compared to control group; and significant alleviation of depression (F=10.849, p=.001) compared to control group

 

 

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Table 1

Literature Review Matrix of Articles Used in Critical Appraisal

Study Citation and Level of Evidence Purpose Design Sample Measurement tool(s)/Instrument(s) Statistical Analysis Key Findings
Berkhof, F., Hertog, N., Uil, S., Kerstjens, H.,& Berg, J. (2013). Azithromycin and cough-specific health status in patients with chronic obstructive pulmonary disease: A randomized control trial. Respiratory Research, 14 (125).

Level II

Assess the effects of prophylactic azithromycin on cough-specific health statuses in COPD patients with chronic productive cough over the course of three months. Single-center parallel group randomized double-blind placebo controlled trial 84 adults > 40 years of age with COPD GOLD stage > 2 and chronic productive cough.

Azithromycin therapy group (n=42) and placebo group (n=42)

Leicester Cough Questionnaire (LCQ)

St. George’s Respiratory Questionnaire (SGRQ)

Short Form 36 (SF-36)

 

 

Intention-to-treat analysis.

Log-rank test.

Kaplan-Meier curves.

Chi-square tests.

ANCOVA analysis.

LCQ scores improved significantly in azithromycin group participants with low baseline scores 1.3 + 0.5 (95% CI 0.3; 2.3, p=0.001). Exacerbation frequency was reduced in azithromycin group.
Lee, H., Kim, S., Sok, S. (2016). Effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression of Korean older adults with mild cognitive impairment in care facilities. Journal of Nursing Scholarship 48 (3) 229-231.

Level III

Examine effects of multivitamin supplements on cognitive function, serum homocysteine level, and depression Quasi-experimental pretest-postest control group

Literature Review Matrix of Articles Used in Critical Appraisal

48 adults > 65 years with mild cognitive impairment (MCI)

Intervention group (n=24); Control group (n=24)

Serum homocysteine levels

Geriatric Depression Scale Short Form Korean Version (GDSSF-K)

Mini Mental State Examination-Korean (MMSE-K)

 

Two group t test

Chi-square test for association

Fisher’s exact test

Literature Review Matrix of Articles Used in Critical Appraisal

Intervention group had significantly increased cognitive function  compared to control group (F=3.624, p=.021); significant decrease serum homocysteine level (F=6.974, p=.001) compared to control group; and significant alleviation of depression (F=10.849, p=.001) compared to control group

 

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